Rózsa Hegedüs Selected Research

gonadotropin-releasing hormone-III

9/2019	Apoptotic Effects of Drug Targeting Conjugates Containing Different GnRH Analogs on Colon Carcinoma Cells.
1/2018	Comparative cell biological study of in vitro antitumor and antimetastatic activity on melanoma cells of GnRH-III-containing conjugates modified with short-chain fatty acids.
1/2016	Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice.
12/2015	[Studying the tumor growth inhibitory effect of modified GnRH-III-anthracycline bioconjugates in subcutaneous vs. orthotopic models in vivo].
5/2015	Modification of daunorubicin-GnRH-III bioconjugates with oligoethylene glycol derivatives to improve solubility and bioavailability for targeted cancer chemotherapy.
10/2012	Enhanced cellular uptake and in vitro antitumor activity of short-chain fatty acid acylated daunorubicin-GnRH-III bioconjugates.

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Rózsa Hegedüs Research Topics

Disease

7	Neoplasms (Cancer) 09/2019 - 01/2011
2	Colonic Neoplasms (Colon Cancer) 09/2019 - 12/2015
2	Colorectal Neoplasms (Colorectal Cancer) 09/2019 - 01/2016
1	COVID-19 01/2022
1	Thrombosis (Thrombus) 01/2022
1	Carcinoma (Carcinomatosis) 09/2019
1	Melanoma (Melanoma, Malignant) 01/2018
1	Breast Neoplasms (Breast Cancer) 05/2015

Drug/Important Bio-Agent (IBA)

6	gonadotropin-releasing hormone-IIIIBA 09/2019 - 10/2012
5	Daunorubicin (Cerubidine)FDA LinkGeneric 09/2019 - 01/2011
4	LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA 09/2019 - 10/2012
3	Pharmaceutical PreparationsIBA 01/2022 - 12/2015
3	Cytostatic AgentsIBA 12/2015 - 10/2012
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 09/2019 - 01/2018
2	Peptides (Polypeptides)IBA 01/2018 - 01/2016
2	Peptide Hormones (Polypeptide Hormones)IBA 01/2018 - 12/2015
2	Volatile Fatty AcidsIBA 01/2018 - 10/2012
2	OximesIBA 01/2016 - 01/2011
1	Proteins (Proteins, Gene)FDA Link 09/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2019
1	Protein Isoforms (Isoforms)IBA 09/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2019
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2018
1	Biological ProductsIBA 01/2018
1	Butyric Acid (Butanoic Acid)IBA 01/2016
1	Hormones (Hormone)IBA 01/2016
1	Acetic Acid (Vinegar)FDA LinkGeneric 01/2016
1	AnthracyclinesIBA 12/2015
1	4-fluorobenzaldehydeIBA 01/2011

Therapy/Procedure

4	Drug Therapy (Chemotherapy) 01/2016 - 01/2011
2	Therapeutics 01/2018 - 12/2015
1	Ligation 01/2011